Topps 75th Anniversary Trading Cards were released by The Topps Company on December 11, 2013. The series reprints iconic non-sport cards from the history of Topps Chewing Gum. Hobby boxes contain 24 packs with 8 cards per pack. Each box guarantees three "Pop Culture Autograph" cards and one buyback card.

The 100-card base set is printed on vintage card stock reminiscent of Topps Chewing Gum cards released prior to 1991. Parallel variations are printed on a modern white stock. Each pack includes one "Rainbow Foil" parallel card. Randomly inserted "Diamond Anniversary" variants are numbered to 75 copies. "Modern Gloss" parallels numbered to 10 are found in approximately 1:224 packs. CMYK printing plates are randomly inserted for each card. A sealed 1/1 blank-back parallel was sold separately by the Topps Vault.

George Reeves appears as Superman from the Adventures of Superman television series. "Metropolis' Hero" was first released as part of the 1965–66 Topps Superman Cards set.

Christopher Reeve appears as Superman in "Night Flight" from Superman: The Movie. The photo cards and stickers were originally issued by Topps Chewing Gum in 1978.

The Test Card subset includes reprints of "Blasting the Python" from Superman in the Jungle, a rare set issued in 1966. The series was penciled by Al Plastino. Inks and color separations were done by Norman Saunders. The 1966 series failed to grab consumer attention in American test markets. Superman in the Jungle was distributed in the UK by A&BC Gum Ltd.

Each 75th Anniversary box contains one gold-foil stamped buyback insert of an original card previously released by Topps. Buybacks from Superman Cards, Superman: The Movie, and Superman II have been observed. The precise number of stamped buyback cards has not been disclosed.